National
The Committee for Skeptical Inquiry (CSI) encourages the critical investigation of paranormal and fringe-science claims from a responsible, scientific point of view and disseminates factual information about the results of such inquiries to the scientific community and the public. It also promotes science and scientific inquiry, critical thinking, science education, and the use of reason in examining important issues.

The Skeptics Society is a scientific and educational organization of scholars, scientists, historians, magicians, professors and teachers, and anyone curious about controversial ideas, extraordinary claims, revolutionary ideas, and the promotion of science. Its mission is to serve as an educational tool for those seeking clarification and viewpoints on those controversial ideas and claims.
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Regional
Washington DC:
National Capital Area Skeptics

Pittsburgh PA:
Steel City Skeptics

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Local
Morgantown WV:
Morgantown Coalition of Reason

Secular Student Alliance at WVU
RELATED ORGANIZATIONS
West Virginians for Science & Reason